Description
Research into the causes of aging, and strategies to delay that process, have gained much ground and attention in recent years. This volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer. Each chapter is written by one or more leaders in the field, and the book presents the current status of this exciting research area and provides an invaluable source of information in a single volume.
Read More
Guarente (Massachusetts Institute of Technology, Cambridge) and colleagues from U. College London and the U. of California, Irvine, introduce 20 chapters capturing the explosion of research in recent years on the aging process and its modulation by genes and diet. Several contributors present findings and the strengths and weaknesses of using mice, yeast, C. elegans, fruit flies, and other model organisms to dissect genetics and molecular aging. Another theme is the influence of diet (e.g., calorie restriction) on potentially extending the life span. Other chapters focus on cell division, metabolism, stress, and DNA repair in aging and age-related diseases such as cancer and Alzheimer's. Aging is also treated from an evolutionary perspective. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
Read Less