Description
The editors write that their intent was to place recent scientific information on the development of endocrine systems into a larger context in which molecular genetics is combined with state-of-the-art understanding of endocrine physiology and the management of endocrine diseases. The reference is meant to help both basic researchers who need information about clinical applications of laboratory investigation, and also practitioners who need to know about the underlying pathophysiology of the endocrinopathies they encounter in the clinical setting. The editors practice at Riley Hospital for Children, Indiana U. School of Medicine. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Leading researchers comprehensively translate all the latest scientific information regarding endocrine physiology and development into an understanding of the clinical pathogenesis, diagnosis, and treatment of endocrine disease. Organized by endocrine system, each section of the book concisely describes the chronological development of the human organism, from the fetal/prenatal period through childhood, adolescence, and in some cases, into adulthood. The prenatal sections review recent discoveries concerning transcription factors, homeobox genes, and human molecular mutations-the basic processes governing prenatal development of the individual endocrine organs-and detail the pathophysiology, clinical characteristics, and treatment of pediatric endocrine disorders.
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