Description
The term tumor markers has traditionally referred to those soluble antigens, hormones, or enzymes that appear in body fluids as a result of an associated clinical cancer. The present volume considers a new class of compounds consisting of cell-associated proteins and nucleic acids, both of which characteristically are not released into serum or other body fluids in any appreciable quantity. Contributions discuss the role(s) of these markers in the mechanism of malignant transformation as well as their effects on clinical outcome, new modes of therapy that molecular approaches are identifying, and issues concerning cost-effective application of the growing number of new tumor markers. Annotation copyright Book News, Inc. Portland, Or.
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In Cellular Cancer Markers leading pathologists and physicians review today's most promising cellular cancer markers, an important emerging class of prognostic markers that can be used in the clinical evaluation of cancer patients. The markers reviewed have been chosen because they are biologically relevant to the growth of cells and possess an accurate and reproducible assay for detection. They also are predictors of tumor behavior, are useful in making clinical decisions, and are cost effective.Cellular Cancer Markers provides a status report for markers of tumor cell activation, proliferation, and longevity that makes possible an informed judgment regarding the value of many newly proposed tumor markers. It also offers insight into the latest approaches to diagnosing cancer and an appreciation of how these marker-based tests can clarify the prognosis of cancer.
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